Working alongside a difficult colleague can be challenging, but adopting a proactive approach can improve the situation. Start by maintaining a respectful and professional tone, regardless of the colleague’s behavior. Setting clear boundaries—particularly if the issues stem from miscommunication or unrealistic demands—can help reduce friction. Focusing on collaboration and common goals, rather than personal differences, keeps the work environment positive. If possible, find areas of agreement to foster goodwill, and document interactions for accountability if issues persist. Seeking support from a manager or HR as a last resort can also be an option. By focusing on respect and professionalism, you can navigate the situation while maintaining your well-being and productivity.